Mutagenic Specificity of N-Nitrosotaurocholic Acid in supF Shuttle Vector Plasmids
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چکیده
منابع مشابه
Mutagenic events induced by 4-hydroxyequilin in supF shuttle vector plasmid propagated in human cells.
Increased incidence of breast, ovarian and endometrial cancers are observed in women receiving estrogen replacement therapy (ERT). Equilin and equilenin are the major components of the widely prescribed drug used for ERT. These equine estrogens are metabolized primarily to 4-hydroxyequilin (4-OHEQ) and 4-hydroxyequilenin, respectively, which are autoxidized to react with DNA, resulting in the v...
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ژورنال
عنوان ژورنال: Genes and Environment
سال: 2009
ISSN: 1880-7062,1880-7046
DOI: 10.3123/jemsge.31.9